Open Positions
The Gene Therapy Institute is committed to establishing a culturally and intellectually diverse environment, encouraging all members of our learning community to reach their full potential. Browse our open positions listed below.
The Department of Neurological Surgery at The Ohio State University College of Medicine is initiating a search for multiple tenure track faculty positions; positions are available at the Assistant, Associate or Full Professor levels. This position works closely with translational scientists across basic science departments and within the Gene Therapy Institute.
The Ohio State University Gene Therapy Institute is a newly organized interdisciplinary community bringing together world-class faculty with diverse expertise in the area of gene therapy research. Successful applicants will join a rapidly growing research environment dedicated to translating laboratory discoveries through preclinical basic science characterization to first in human clinical testing. Gene Therapy Institute faculty are building a multi-disciplinary, collaborative, research environment to rapidly advance therapies to treat disease. Individuals with research interests in novel gene therapy approaches (viral, non-viral) to manipulate brain function in health and disease are encouraged to apply.
Qualifications
Required: Candidates should have a Ph.D., and/or M.D. degree, post-doctoral training, a commitment to basic and/or translational neuroscience, and a history of strong research productivity. Individuals will be evaluated on their ability to establish innovative independent research programs as well as develop collaborative ideas of focus with existing programs.
Applications should include a Research Statement detailing planned independent research, description of previous research experience and a detailed curriculum vitae (CV).
Any questions can be directed to the chair of the search, Dr. Krystof Bankiewicz, through Kaitlen Knight at Kaitlen.Knight@osumc.edu.
Staff Positions
Job Description Summary
Research Scientist to participate in the development and implementation of a nationally competitive program investigating translational pre-clinical studies in the development of AAV, drug-loaded liposomes, mRNA-based nanoparticles-based gene therapies for central nervous system disorders such as Parkinson’s disease, Huntington’s disease, AADC deficiency, Alzheimer’s disease, lysosomal storage disorders, hearing loss, and depression within the Department of Neurological Surgery at The Ohio State University.
Duties will include study design; protocol and report writing; assistance in the set-up of new clinical trials; identification and pursuit of new research directions; coordinating writing and submission of grant proposals as co-investigator to extramural funding agencies to obtain significant salary and research support; develops, adopts and implements new laboratory methods; develops hypotheses and experimental approaches to test these hypotheses; plans, designs and conducts complex experiments; extracts, compiles, analyzes and evaluates data to establish relevance to the problems being evaluated; administers grants; directs and manages grant budgets; writes manuscripts, articles, abstracts and research reports for publication in peer-reviewed journals; attends and presents research findings at national and international scientific conferences; develops and conducts educational workshops, lectures and seminars; collaborates with other researchers in determining research priorities and planning programs of research; trains, mentors and supervises junior investigators, postdocs, graduate students, and research staff in the laboratory.
Minimum Education and Skills/Experience Required/Desired
Doctorate orequivalent combination of education and experience. Experience in a progressively responsible research capacity required; demonstrated publication record in peer-reviewed journals required. Requires successful completion of a background check.
Job Description Summary
Research Associate who participates in planning, design, execution, and management of all in-vivo research studies and activities in a research laboratory investigating translational pre-clinical studies in the development of AAV, drug-loaded liposomes, mRNA-based nanoparticles-based gene therapies for central nervous system disorders such as Parkinson’s disease, Huntington’s disease, AADC deficiency, Alzheimer’s disease, lysosomal storage disorders, hearing loss, and depression in the Department of Neurological Surgery; participates in the execution of ongoing research projects; assists in stereotaxic brain surgery in rodents & non-human primates, including pre- and post-operative care; proficient in specialized necropsy techniques in small and large animals with the ability to lead necropsy function in the lab; leads efficient and high-quality sample collection, processing, tissue preservation and tissue trimming according to study protocols; assists with histology duties such as tissue processing, embedding, frozen sections, sorting, cutting, filing, reagent preparation, special stains, and staining slides of tissue samples; collects, analyzes, and interprets research data; assists in establishment of controls, criteria and research standards; collects and maintains preclinical study data effectively and efficiently for FDA submission; creates and keeps detailed and organized records of all in-vivo research activities across various studies; performs PCR and electrophoresis gels for mice genotypic; has extensive knowledge in murine animal model experimentation, including injections (intramuscular, intraperitoneal, intravenous (tail vein and RO)), as well as blood collection techniques including cardiac puncture and cheek bleed, and tissue collection; murine colony management including breeding and weaning, mice tagging identification, monthly cage counting, record keeping, and euthanization; maintains accuracy of and compliance to IACUC protocol and ensures GLP conditions in IND-enabling in-vivo research studies; works closely with laboratory veterinarians and IACUC committee and staff to efficiently update the IACUC protocol as new studies are proposed and assists collaborators with IACUC protocol creation and adherence; manages lab spaces in accordance with IACUC and EHS regulations and leads IACUC and controlled substance inspections; assists in the preparation of research papers and manuscripts for publication and presentation at national and conferences and workshops, and in the writing of project reports, articles, and other documents; assists principal investigator in the preparation of proposals to obtain new or renewal of extramural funding in support of research; provides updates to PI and laboratory manager on progress of research.
Minimum Education and Skills/Experience Required/Desired
Bachelor’s degree in an appropriate biological/health science or an equivalent combination of education and experience is required. 1-3 years of relevant experience required. Ability to translate, adapt and apply academic and/or practical knowledge in the conduct of biological/health science research is required. Experience in a biological/health science research capacity is preferred. Requires successful completion of a background check; qualified candidates may be asked to complete a pre-employment physical, including a drug screen.
Postdoctoral Positions
The Gene Therapy Institute at The Ohio State University is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status or protected veteran status.